New Step by Step Map For cees dekker
New Step by Step Map For cees dekker
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‘The second is nanopores, which is our oldest line of study and which has now triggered DNA sequencers according to nanopores. We pull person DNA strands via a nanopore and will then browse from the nucleotide sequence. Quite not long ago, we even managed to read through out an individual protein for the first time making use of this technique. But this line of research is don't just about acquiring instruments, but in addition about actual biological questions.
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Dynamics of initiation, termination and reinitiation of DNA translocation through the motor protein EcoR124I
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
This yielded a breakthrough. Inside of only a few months, we ended up capable of evaluate transport by a person one-walled carbon nanotube. Depending on small-temperature experiments by an excellent PhD student in my group, Sander Tans (now a valued colleague and professor at Delft College of Technological innovation with an Energetic investigate lab at AMOLF in Amsterdam), we showed that carbon nanotubes ended up genuine quantum wires with incredibly long (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
‘To start with we checked out Organic methods by using a physical check out and acted on The idea of your tools we understood. It took a several years before we began Doing work extra on the big biological concerns. I then started to simply call it nanobiology, a time period that did not exist at the time.
2011, initial in vitro measurements of transport throughout one biomimetic nuclear pore advanced; progress of multiplexed magnetic tweezers for kilo-molecule experiments; and solved the mechanism of homology recognition in DNA homologous recombination
The rotors harness Electrical power from a nanoscale water and ion stream that is certainly generated by a static chemical or electrochemical opportunity gradient while in the nanopore, which can be established via a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological ailments, suggesting approaches to constructing Strength-transducing motors at nanoscale interfaces.
It was for the duration of this era that Dekker completed exploration on magnetic spin units and on sounds in superconductors and semiconductors.
An integrated microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
Nanoscientist Cees Dekker is surely an amiable and flamboyant guy who appears A great deal youthful as opposed to 62 years he actually is – modern glasses, psychedelic shirt, engaging smile – although not one particular to waste time. He will take his time, but no more than vital.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij met enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart style and design in 2005. (nl)